What is PRP for skin?
PRP is plasma separated from a blood sample so that its platelet count is higher, then placed into the skin with fine needles or with microneedling. Platelets carry growth factors involved in tissue repair, and the idea is that this natural content supports the skin.
Platelets are blood cells that help clotting and also carry several growth factors involved in wound healing. The reasoning behind PRP is that when a concentrated form of these factors is given to the skin, it may support the tissue's own renewal processes. In aesthetic use it is considered for fine lines, skin quality, a dull look and thin-skinned areas such as under the eyes.
The level of evidence differs by area and purpose. Studies on skin appearance use different methods, kits and session plans, so results cannot be presented as one standard. It is important to keep expectations realistic and to know that the effect is gradual and varies from person to person.
How is PRP prepared and applied?
A small amount of blood is taken from the arm, spun in a special tube to separate the plasma, and the platelet-rich part is applied to the skin by injection or microneedling. The process is usually completed in a short appointment including preparation.
Before the procedure the doctor reviews your health history, your medicines and your skin. The blood draw is similar to a routine blood test. The blood is spun in a closed tube so that cells and plasma separate into layers, and the part to be used is collected. The kit and steps may differ according to the manufacturer and the clinic protocol.
A surface numbing cream may be applied first. The plasma is given in small amounts into the skin, or spread on the surface and carried in with microneedling. Redness, mild swelling and pinpoint bruising can follow and usually ease within a few days. Avoiding make-up and strenuous exercise on the first day is often advised; your doctor gives the details.
How does PRP differ from mesotherapy?
The clearest difference is the source of the content. Mesotherapy uses ready-made products such as hyaluronic acid, amino acids or vitamins; PRP uses plasma prepared from your own blood. The technique can look similar, but the mechanism and expectations differ.
With ready-made products the content is defined and product information comes from the manufacturer. With PRP the content varies from person to person and with the preparation; platelet concentration can differ even in the same person on different days. For this reason PRP cannot fairly be compared with a standard product.
Because it is prepared from your own blood, a reaction to the product itself is less expected, but that does not mean the procedure carries no risk. Bruising, swelling, infection and, rarely, problems linked to hygiene during preparation can occur. Mesotherapy and skin booster options made with ready-made products are described on a separate page.
Who should not have PRP?
PRP is usually postponed or not advised with blood disorders, conditions affecting platelet count or function, active infection, active skin disease in the area, use of blood thinners, and during pregnancy or breastfeeding. The doctor makes the decision.
In people with a low platelet count or a clotting disorder, both preparing and applying PRP can be problematic. Blood thinners, some pain relievers and supplements can increase bruising; do not stop them on your own, but tell your doctor. With active acne, cold sores, an eczema flare or infection, the procedure is usually left until healing.
Elective aesthetic procedures are usually postponed in pregnancy and breastfeeding. Mention a history of cancer, an autoimmune disease or treatment that suppresses immunity at the consultation. If you recently had a laser, peel or another injection, the timing may be rearranged.
How many sessions are needed and how long do results last?
Session number and interval vary with the person, skin condition and protocol; a short course a few weeks apart is common. The effect appears gradually and its duration differs between people. The degree of result cannot be predicted in advance.
For skin quality, change is usually noticed gradually over weeks rather than in the first days. How long it lasts depends on age, skin structure, sun exposure, smoking and care habits. Maintenance sessions may be discussed; whether they are needed is judged after results are observed, not at the first plan.
Marked sagging, deep wrinkles or volume loss are not problems PRP resolves; other approaches are discussed for those. The general approach to session planning is covered on the mesotherapy sessions page and product types on the skin booster page. The suitable method is decided at the consultation in Nişantaşı, looking at your skin and expectations together.
Frequently asked questions
Is the PRP procedure painful?
Pain perception varies between people. A surface numbing cream is usually applied, and most people find the procedure tolerable. You may feel pricking with the fine needles, plus tenderness and warmth afterwards. If you are sensitive to pain, tell your doctor beforehand.
How long does redness last after PRP?
In most people redness and mild swelling ease within hours to a few days. Pinpoint bruises can last longer. If symptoms increase, pain becomes severe or a fever develops, contact the treating doctor without delay.
Does PRP work the same way in everyone?
No. The content of the plasma varies with the person, the day and the preparation method, and the skin's response depends on age, skin structure and lifestyle. The result therefore cannot be set in advance, and comparisons can be misleading.
Can PRP be done during pregnancy?
Elective aesthetic injections are usually postponed in pregnancy and breastfeeding. During this time it is more appropriate to follow your doctor's skin-care advice.
What should be avoided after PRP?
Strenuous exercise, sauna, steam rooms, alcohol and strong active products are often avoided for the first days, and sun protection matters. The exact list is given by the doctor according to how the treatment was applied and your skin.
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This content is for general information and does not replace a personal medical assessment.